Abstract: This study aimed to explore the role of information systems in healthcare management within organizations. The objectives were to investigate how information systems improve patient care delivery, enhance clinical decision-making, and streamline healthcare operations. A survey research design was chosen to gather quantitative data from a sample of 270 respondents, selected using the Taro Yamane formula to ensure representation across healthcare providers and facilities. The study focused on a case study of a hospital in Enugu, known for its electronic health records (EHR) system and telemedicine capabilities. Conducted in Enugu, the reliability coefficient score was determined to be 0.87, indicating strong internal consistency in survey responses. The findings indicated that healthcare information systems enhance medical data accessibility, support evidence-based practices, and improve patient outcomes. The study recommends that healthcare organizations invest in interoperable EHR systems, integrate telemedicine technologies, and prioritize data security measures to enhance healthcare delivery quality, patient satisfaction, and operational efficiencies.
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